COLON CANCER
  • Bacteria in cancer unmasked
    Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This… Read more »
  • Microbial signature of colorectal cancer-associated mutations identified in new study
    Researchers have connected KRAS mutations in colorectal cancer to microbial signatures in the gut. Read more »
  • Bacteria subtype linked to growth in up to 50% of human colorectal cancers
    Researchers have found that a specific subtype of a microbe commonly found in the mouth is able to travel to the gut and grow within colorectal cancer tumors. This microbe is also a culprit for driving cancer progression and leads to poorer patient outcomes after cancer treatment. The findings could… Read more »
  • A smart molecule beats the mutation behind most pancreatic cancer
    Researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition. Read more »
  • How early-stage cancer cells hide from the immune system
    Researchers found that precancerous colon cells can avoid immune detection by turning on a gene called SOX17, which allows them to become essentially invisible to the immune system. Read more »
  • Study demonstrates benefit of precision medicine based on race/ethnicity
    A new study highlights racial disparities in a subset of cancer patients and, using advanced biomedical research technology, provides evidence for those differences at the molecular level. Read more »
  • Promising anticancer drug targeting KRAS protein
    A team of scientists has successfully developed a groundbreaking targeted therapy that hones in on the KRAS protein that drives some of the deadliest human cancers, including pancreatic, lung and colon tumors. Their findings suggest that a novel inhibitor drug could be used to target KRAS G12D, a subset of… Read more »
  • Cholesterol-lowering therapy may hinder aggressive type of colorectal tumor
    Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study. The finding points to the possibility of using cholesterol-lowering drugs to prevent or treat such tumors. Read more »
  • Could eating turkey ease colitis?
    According to data in mice, extra tryptophan could reduce the risk of future colitis flares. Read more »
  • Pancreatic cancer discovery opens the door for new clinical trial
    A new scientific finding is the foundation for the first clinical trial in the U.S. to study an experimental drug's ability to fight pancreatic cancer with metastasis to the liver.   Read more »
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